Ion Channels (Topics in Medicinal Chemistry

عضو ذهبى

Ion Channels (Topics in
Medicinal Chemistry

Ion Channels (Topics in Medicinal Chemistry)

By Bernard Fermini, Birgit Priest

Publisher: Springer

Number Of Pages: 171

Publication Date: 2008-09-01

ISBN-10 / ASIN: 3540797289

ISBN-13 / EAN: 9783540797289

Binding: Hardcover

Product Description:

Ion channels play a vital role in basic physiological functions such as
generation of electrical activity in nerves and muscle, control of
cardiac excitability, intracellular signaling, hormone secretion, cell
proliferation and many other biological processes. Because of their
prevalence and the critical role they play in virtually all tissue types
and organs, ion channels are also involved in a number of
pathophysiological conditions. The aim of this volume is to review
recent advances in the field of ion channel related diseases. Following
an overview chapter summarizing the current state of ion channel
screening technologies, five topics covering areas such as cancer,
cardiac arrhythmias, cystic fibrosis, and pain have been selected, and
the current state of knowledge is presented by leading experts in their
field. Each chapter is structured to cover the biological rationale for
the target, the current status in the development of agents to treat the
disease, and future prospects and challenges facing each therapeutic
area. The reader will receive a critical overview covering the progress
made in the rapidly developing and complex field of ion channels and
diseases.

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